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MRC Cancer Unit


Dr Jacqui Shields

Research Profile


Jacqui Shields studied Pathology and Microbiology at the University of Bristol. She then went on to complete her PhD in tumour microcirculation in the Department of Physiology at Bristol, where her interest in tumour-associated lymphatic vessels began.

In 2005, she joined the laboratory of Professor Melody Swartz, at the Institute of Bioengineering at EPFL in Switzerland to pursue her postdoctoral training, gaining expertise in lymphatic functionality and how this could relate to tumour progression. During this time, Jacqui was awarded the "Fondation Latsis Internationale" Prize for her work on understanding how tumour cells sense and exploit functional, draining lymphatics to promote metastasis. In 2008 she was awarded the Servier Award for research of significant contribution to the field of microcirculation. Jacqui’s research has helped to elucidate links between lymphatic function and lymphatic growth factors with the processes of tumour progression and metastasis.

Jacqui moved to the MRC Cancer Unit in June 2011, progressing to tenure track programme leader in 2013 and receiving tenure in 2019. Her research programme aims to elucidate how the tumour stroma regulates immune activity to promote carcinogenesis from its earliest stages, using this knowledge to develop new approaches for early detection, risk stratification, or therapy