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The MRC Cancer Unit’s mission is to advance understanding of the earliest steps in the development of cancer, and use this knowledge to improve the early detection of cancer, to identify individuals who are most at risk of developing cancer, and to develop new approaches for the treatment of cancer, through the creation of innovative technologies.

For details of our work, please visit the research profiles of group leaders by clicking on the names in the side menu or the list of topic areas below.


Rebecca Fitzgerald

Professor Rebecca Fitzgerald

Oesophago-gastric adenocarcinoma: understanding disease pathogenesis and applications to earlier diagnosis

Christian Frezza

Dr Christian Frezza
Cancer Metabolism

Phil Jones

Professor Phil Jones
Cell fate and cancer

Carla Martins

Dr Carla Martins
Modelling tumour development and therapy

Jacqui Shields

Dr Jacqui Shields
Stroma function in the tumour microenvironment

Sakari Vanharanta

Dr Sakari Vanharanta
Molecular origins of metastatic cancer phenotypes

Ashok Venkitaraman

Professor Ashok Venkitaraman
1)Tumour suppressor mechanisms in the control of genome stability 2)Therapeutic target discovery and systems microscopy (w/ Grahame McKenzie and Alessandro Esposito).

Shamith SamarajiwaDr Shamith Samarajiwa

Deciphering cellular information networks underlying early carcinogenesis using integrative computational and data science approaches


Dr Benjamin Hall
Modelling the decision making processes of cancer


Dr Serena Nil-Zainal

Exploring the physiology of mutagenesis using experimental and computational approaches